Extracts and novel molecules such as polysaccharides, tannins, terpenes, lignans. Sarsaparilla smilax glabra rhizome extract activates redox. Usage of herbs as a source of food, medicine, fragrance, flavour. A polysaccharidepeptide with mercury clearance activity.
Discovery of naturally occurring aurones that are potent. The role of extractives in the natural durability of the. Frontiers saponins and flavonoids from adzuki bean. Smilax glabra rhizoma affects the pharmacokinetics and tissue. Smilax glabra rhizoma sgr has the effect of detoxification and immunoregulation, and has been used as. Biodiversity and conservation of medicinal and aromatic. It is also a key ingredient in the chinese medical dessert guilinggao, which makes use of its property to set certain kinds of jelly chemical composition. The root tubes of which furnish the drug known as china root. We have identified naturally occurring 2benzylidenebenzofuran3ones aurones as new templates for nonnucleoside hepatitis c virus hcv rnadependent rna polymerase rdrp inhibitors. Smilax glabra herb uses, benefits, cures, side effects. In the present study, we found that the supernatant of watersoluble extract from sgr sw could promote adhesion, inhibit migration and invasion of. The increased prevalence of allergy and the hygiene hypothesis. It was established in 2001, succeeding from the former. Content determination of total tannin in smilax glabra with reddish brown and offwhite colored cross section.
This traditional formulation has been used as folk medicine to treat breast cancer patients, balance element in the patients body or increase their. The plants belonging to this genus are found throughout asia, europe, oceania. Many chinese herbs have been tested against herpes simplex virus hsv in search for new antiherpetic agents. Recent advances in the discovery of novel antiherpetic. Smilax glabra, and evaluation of its antiinflammatory effect and probable underlying mechanism in lipopolysaccharideinduced raw264.
Antioxidant and antiinflammatory activities of phenolic. Nine new meroterpenes 19 and one new dioxolanone derivative 10, along with seven known compounds 1117, were isolated from solid cultures of the endophytic fungus guignardia sp. Help on accessing alternative formats, such as portable document format pdf, microsoft word and powerpoint ppt files, can be obtained in the alternate format help section. A new isoflavone, 7,6dihydroxy3methoxyisoflavone, has been isolated from the roots of smilax glabra. Antioxidant and antiinflammatory activities of phenolicenriched. In this study, antimutagenic, antimicrobial and antioxidant activities of smilax excelsa l. Smilax glabra rhizoma sgr has the effect of detoxification and immunoregulation, and has been used as both food and folk medicine in many. Sarsaparilla, also known as smilax glabra rhizome sgr, was shown to modulate immunity, protect against liver injury, lower blood glucose and suppress cancer.
Optimization of astilbin extraction from the rhizome of. Dihydroflavonol glycosides astilbin, neoastilbin, isoastilbin, neoisoastilbin, 2r, 3rtaxifolin3obetad pyranoglucoside have. The rhizome of smilax glabra has been used for a long time as both food and folk medicine in many countries. Evidencebased complementary and alternative medicine. The record derives from wcsp data supplied on 20120326 which reports it as an accepted name record 289290 with original publication details. Smilax is the member of the lily family which is used for medicinal uses. Astilbin is a avonoid compound isolated smilax glabra roxb. Chemical constituents from the rhizomes of smilax glabra. Smilax glabra has not been shown to treat or prevent cancer. Smilax glabra rhizoma affects the pharmacokinetics and. The roots and berries have various health benefits. Smilax glabra memorial sloan kettering cancer center.
Effect of standardized decoction of nigella sativa seed, hemidesmus indicus root and smilax glabra rhizome on the expression of p53 and p21 genes in human hepatoma cells hepg2 and mouse liver. Methotrexate mtx is a widely used immunosuppressant and anticancer agent with high toxicity. Plants for damp or wet areas plants marked with an are more tolerant of very wet or periodically flooded conditions. It is found in the south indian states namely andrapradesh, tamilnadu and karnataka 8. Smilax chinensis l liliaceae is a deciduous climber with rounded leaves and red berries.
Glucosidase inhibitory activity of the extracts and major phytochemical components of smilax glabra roxb, 10. It is native to china, the himalayas, and indochina. Antimutagenic and multibiological activities of smilax. October 89, 1998 zurich, switzerland molecules 1998, 3, 148 pdf. Hypoglycemic effect of the rhizomes of smilax glabra in.
Yildiz et al in their recent article, published in the september issue of the world journal of gastroenterology, have clearly highlighted the efficacy of nigella sativa n. Pdf antioxidant and antiinflammatory activities of phenolic. Phytochemical screening of the methanol extract of root. Antibreast cancer activity of thai herbal medicine. This study was carried out to determine the chemoprotective potential of a polyherbal aqueous decoction comprised of nigella sativa seeds, hemidesmus indicus roots, and smilax. It is used as an aid for health problems such as skin ailments and syphilis. Smilax glabra, the chinaroot, tufuling or sarsaparilla, is a plant species in the genus smilax. The present study focused on the active constituents from the rhizome of. Localization of organic cation transporters oct1 and oct2.
Long is a protected area zone in northeastern vietnam. The methanol extract of rhizomes of smilax glabra roxburgh sm, 100 mgkg body weight reduced the blood glucose of normal mice 4 h after intraperitoneal administration p smilax. Executive editor inchief chen hualan managing editor. The emerging field of herbal products industry holds a great potential to the economic development of the indian region. As an herbal medicine, adzuki bean has been practiced since the tang dynasty of china to maintain health and control weight. Using 4 groups of smilax glabra from different areas, weigh about 1. A new isoflavone from smilax glabra molecules 1998, 3, 145147 pdf format, 19k announcement. However, its effects on cancer cell adhesion, migration and invasion were unclear. It is associated to the smilacaceae family and a kind of species found in the smilax genus. Pdf smilax smilacaceae is a genus of about 350 species, found in. Sgr increased pgp mrna expression in the small intestine by 2. When selecting plants using this list, remember that a number of factors determine.
The effect of sgr on gene expression demonstrated a time, transporter and tissuedependent manner. Historical medical sources can be still queried for forgotten cures and remedies. The rhizomes of smilax glabra sg has long been used in traditional. Emerging clinical and therapeutic applications of nigella. Plants for damp or wet areas lockwoods greenhouses. Antioxidant and antiinflammatory activities of phenolicenriched extracts of smilax glabra. In our study, the concentration of no in ppstreated cells reached 58. Traditional chinese medicine has dealt with lues venerea syphilis. Research on the different composition of smilax glabra. Smilax glabra is known as tufuling in traditional chinese medicine. Chinese vegetative materia medica in a venereological. Smilax smilacaceae is a genus of about 350 species, found in temperate, tropical and subtropical zones worldwide.
Bmc complementary medicine and therapies home page. A polysaccharidepeptide with mercury clearance activity from dried fruiting bodies of maitake mushroom grifola frondosa. Synergistic antifungal meroterpenes and dioxolanone. M in medium and the coculture microenvironment, respectively, and was higher than that resulting from treatment with a. The root has been used in combination with other herbs to treat various types of infections and inflammatory conditions. Pdf phenolic compounds in genus smilax sarsaparilla. Second annual conference on strategies and techniques for identification of novel bioactive compounds. The present study focused on the active constituents from the rhizome of s. Inhibitory effects of chemical compounds isolated from the. Sarsaparilla smilax glabra rhizome extract inhibits migration and invasion of cancer cells by suppressing tgf. Sarsaparilla smilax glabra rhizome exerts growth inhibitory effect on multiple cancer cells in vitro and in vivo, and redoxdependent. Astilbin undergoes extensive biotransformation speci cally due to enzyme catecholomethyl transferase. Sarsaparilla smilax glabra rhizome extract inhibits. Guignardones ps, new meroterpenoids from the endophytic fungus guignardia mangiferae a348 derived from the medicinal plant smilax glabra.
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